The Graeme Clark Institute draws on the collective medical, engineering and scientific capabilities of the University of Melbourne, supported by healthcare and research partners from the Melbourne Biomedical Precinct and beyond.
Key areas of biomedical engineering expertise within the Institute include tissue engineering, nanomedicine, biomimetics, biomechanics, medical bionics, implant systems, biosignals, medical robotics, mechanobiology, computational engineering, systems and synthetic biology, biomedical imaging, and health informatics.
Neuro-electronics therapy and bionics
The translation of neural-electronic interface research into improved health outcomes is gathering pace, with advances in implantable miniaturised electronic devices that record or stimulate nerve signals.
Advances in 3D printing and the miniaturisation of devices are revolutionising medical technologies, providing the ability to personalise healthcare and improve the wellbeing of people around the world as never before.
Drug screening technologies and mechano-pharmacology
The field of ‘tissue-on-a-chip’ and ‘organ-on-a-dish’ is evolving rapidly and is opening opportunities in drug discovery, toxin screening and disease modelling.
The research focus of this program is in the area of kinematics and dynamics of robotics mechanisms (its modelling, analysis and manipulation) and their applications primarily in biomedical and clinical tasks.
Assistive and rehabilitation robotics
This project focuses on the study of robotics technology in the investigating human motor systems and the clinical rehabilitation of people with motion impairment, such as in post-stroke patients.
Technologies for the management of Parkinson’s Disease
The research is focussed on the measurement movement disorders including Parkinson’s Disease (PD), to assist in their management
Biomaterials, bio-fabrication and regenerative medicine
The combination of materials science, materials engineering and clinical expertise is developing engineered tissues to replace or support the repair of natural tissue.
Computational modeling for cardiovascular disease
Advances in cardiovascular and stent technology are providing new options to support the operation of cardiac systems, to monitor performance and to deliver medication.
Biomedical imaging technologies
Advanced imaging technologies will lead to improved diagnosis and treatment of a wide range of neurological disorders.
Nano-materials and drug-delivery systems
Novel nano-materials that interact with the body’s biological processes at the cellular level are providing new, targeted drug-delivery opportunities.
Fluid dynamic modelling for pharmaceutical manufacturing
The program is developing computational fluid dynamics models to understand and predict the behaviour of platelets in typical blood flow and during clotting.
Polymeric drugs for combating anti-microbial resistance
Nature’s prowess in making molecules with astounding properties, such as DNA, serves as important inspiration to Professor Greg Qiao.
Synthetic biology approaches to designer-stem-cell-based therapies
This research develops experimental and computational approaches to apply engineering design and analysis principles to study existing biological cellular systems and to create new cellular systems with user-defined properties and functions.
3D structural support for High throughput compound and molecular screening
The development of three dimensional (3D), spheroid or organoid cellular cultures for the study of cellular function, therapeutic development and biomarker discovery, has been the cornerstone of cancer research for many years.
Reverse engineering the brain
The human brain is thought to be a predictive, efficient, and adaptive machine. The goal of this research program is to understand how the brain’s circuitry implements the mechanisms which enable us to perceive the world through our senses, learn, and make inferences and decisions.
Next generation therapies for hearing and balance
Human hearing and balance are two of the most poorly understood senses at a molecular level. This is largely the result of inaccessibility to the adult inner ear via biopsy, resulting in a lack of human tissue available for studying the specialised cell types that reside within it.
Multicellular Systems Biology
This program uses Mathematical and Computational methods to better understand multicellular biological systems with a focus on the influence of biomechanics on tissue and organ development and disease.